4ZWB

Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Solute carrier family 2, facilitated glucose transporter member 3	polymer	518	56474.5	1	UniProt (P11169) Pfam (PF00083)	Homo sapiens (Human)	Glucose transporter type 3,brain,GLUT-3
2	B (B)	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	1	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose
3	C (A)	water	water		18.0	36	Chemie (HOH)

Sequence modifications

A: 1 - 496 (UniProt: P11169)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Asp -8	-	expression tag
Glu -7	-	expression tag
Val -6	-	expression tag
Asp -5	-	expression tag
Ala -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag
Thr 43	Asn 43	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	56474.5
Branched	Number of molecules	1
	Total formula weight	342.3
All*	Total formula weight	56816.8

*Water molecules are not included.