4ZVZ
Co-crystal structures of PP5 in complex with 5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine/threonine-protein phosphatase 5 | polymer | 333 | 37887.0 | 4 | UniProt (P53041) Pfam (PF08321) Pfam (PF00149) | Homo sapiens (Human) | PP5,Protein phosphatase T,PPT |
| 2 | E, F, H, I, K... (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
| 3 | G, J, M, R (A, B, C, D) | (1R,2S,3R,4S,5S)-5-(propoxymethyl)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid | non-polymer | 258.3 | 4 | Chemie (4TF) | |||
| 4 | N (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | O, S (C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 169 - 499 (UniProt: P53041)
| PDB | External Database | Details |
|---|---|---|
| Gly 167 | - | expression tag |
| Ala 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 151548.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1707.8 | |
| All* | Total formula weight | 153255.9 |
