4ZVU
Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Caspase-7 | polymer | 198 | 22189.2 | 2 | UniProt (P55210) Pfam (PF00656) | Homo sapiens (Human) | CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3 |
| 2 | B, D (B, D) | Caspase-7 | polymer | 113 | 13223.8 | 2 | UniProt (P55210) Pfam (PF00656) | Homo sapiens (Human) | CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3 |
| 3 | E, F (E, F) | Tetrapeptide Inhibitor Ac-VEID-CHO | polymer | 5 | 486.6 | 2 | BIRD (PRD_000929) | synthetic construct | |
| 4 | G, H, I, J, K (A, B, C, D, E) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
B, D: 199 - 303 (UniProt: P55210)
| PDB | External Database | Details |
|---|---|---|
| Leu 304 | - | expression tag |
| Glu 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
| His 311 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 71799.1 | |
| All* | Total formula weight | 71799.1 |
