4ZVU

Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Caspase-7	polymer	198	22189.2	2	UniProt (P55210) Pfam (PF00656)	Homo sapiens (Human)	CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3
2	B, D (B, D)	Caspase-7	polymer	113	13223.8	2	UniProt (P55210) Pfam (PF00656)	Homo sapiens (Human)	CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3
3	E, F (E, F)	Tetrapeptide Inhibitor Ac-VEID-CHO	polymer	5	486.6	2	BIRD (PRD_000929)	synthetic construct
4	G, H, I, J, K (A, B, C, D, E)	water	water		18.0	31	Chemie (HOH)

Sequence modifications

B, D: 199 - 303 (UniProt: P55210)

PDB	External Database	Details
Leu 304	-	expression tag
Glu 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	71799.1
All*	Total formula weight	71799.1

*Water molecules are not included.