4ZUD

Crystal Structure of Human Angiotensin Receptor in Complex with Inverse Agonist Olmesartan at 2.8A resolution.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chimera protein of Soluble cytochrome b562 and Type-1 angiotensin II receptor	polymer	410	46722.0	1	UniProt (P0ABE7) UniProt (P30556) Pfam (PF07361) Pfam (PF00001)	Escherichia coli	Cytochrome b-562,AT1AR,AT1BR,Angiotensin II type-1 receptor,AT1,AT1AR,AT1BR,Angiotensin II type-1 receptor,AT1
2	B (A)	Olmesartan	non-polymer		446.5	1	Chemie (OLM)

Sequence modifications

A: 1001 - 1106 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 1007	Met 29	engineered mutation
Ile 1102	His 124	engineered mutation
Leu 1106	Arg 128	engineered mutation

A: 12 - 16 (UniProt: P30556)
A: 17 - 315 (UniProt: P30556)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	46722.0
Non-Polymers*	Number of molecules	1
	Total formula weight	446.5
All*	Total formula weight	47168.5

*Water molecules are not included.