4ZU1

Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with O-acetyl serine and peptide inhibitor

Replaces:  4MIL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (X)	Cysteine synthase	polymer	332	35460.4	1	UniProt (P45040) Pfam (PF00291)	Haemophilus influenzae KW20	CSase,O-acetylserine (thiol)-lyase,OAS-TL,O-acetylserine sulfhydrylase
2	B (A)	C-terminal peptide from Serine acetyltransferase	polymer	10	1177.2	1	UniProt (P29847)	Salmonella typhimurium LT2	SAT,Serine transacetylase
3	C (X)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D (A)	O-ACETYLSERINE	non-polymer		147.1	1	Chemie (OAS)
5	E, F (X, A)	water	water		18.0	32	Chemie (HOH)

Sequence modifications

X: 1 - 316 (UniProt: P45040)

PDB	External Database	Details
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36637.6
Non-Polymers*	Number of molecules	2
	Total formula weight	239.2
All*	Total formula weight	36876.9

*Water molecules are not included.