4ZRI
Crystal structure of Merlin-FERM and Lats2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Merlin | polymer | 324 | 38028.9 | 2 | UniProt (P35240) Pfam (PF09379) Pfam (PF00373) Pfam (PF09380) | Homo sapiens (Human) | Moesin-ezrin-radixin-like protein,Neurofibromin-2,Schwannomerlin,Schwannomin |
| 2 | C, D (C, D) | Serine/threonine-protein kinase LATS2 | polymer | 32 | 3516.0 | 2 | UniProt (Q9NRM7) | Homo sapiens (Human) | Kinase phosphorylated during mitosis protein,Large tumor suppressor homolog 2,Serine/threonine-protein kinase kpm,Warts-like kinase |
| 3 | E, F (A, B) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 320 (UniProt: P35240)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83089.8 | |
| All* | Total formula weight | 83089.8 |
