4ZR5
Soluble rabbit neprilysin in complex with phosphoramidon
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Neprilysin | polymer | 696 | 79479.4 | 2 | UniProt (P08049) Pfam (PF05649) Pfam (PF01431) In PDB | Oryctolagus cuniculus (Rabbit) | Atriopeptidase,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE |
| 2 | C, D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN | non-polymer | 543.5 | 2 | BIRD (PRD_000638) Chemie (RDF) | |||
| 5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A, B: 55 - 750 (UniProt: P08049)
| PDB | External Database | Details |
|---|---|---|
| Lys 194 | Asn 194 | see remark 999 |
| Ser 363 | Phe 363 | see remark 999 |
| Leu 367 | Phe 367 | see remark 999 |
| Met 371 | Phe 371 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 158958.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1660.2 | |
| All* | Total formula weight | 162316.6 |
