4ZQ9

X-ray structure of AAV-2 OBD bound to AAVS1 site 3:1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Protein Rep68	polymer	211	24412.7	3	UniProt (P03132) Pfam (PF08724) In PDB	Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2)
2	D	DNA (5'-D(*GP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*GP*GP*GP*C)-3')	polymer	21	6408.1	1		Homo sapiens
3	E	DNA (5'-D(*CP*GP*CP*CP*CP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*G)-3')	polymer	21	6484.2	1		Homo sapiens
4	A, C	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
5		water	water		18.0	58	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 208 (UniProt: P03132)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Glu 17	Gly 17	conflict
Ser 151	Cys 151	engineered mutation
Phe 156	Tyr 156	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	86130.3
Non-Polymers*	Number of molecules	2
	Total formula weight	109.9
All*	Total formula weight	86240.2

*Water molecules are not included.