4ZOM
RORgamma in complex with inverse agonist 4j.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Nuclear receptor ROR-gamma | polymer | 225 | 26160.2 | 4 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | E, F, G, H (A, B, C, D) | N-{4-[3-(acetylamino)-1-(propan-2-yl)-1H-pyrazol-5-yl]-2-[(1R,5S)-3-azabicyclo[3.1.0]hex-3-yl]phenyl}-2-chloro-6-fluoro-N-methylbenzamide | non-polymer | 510.0 | 4 | Chemie (4Q3) | |||
| 3 | I, J (A, B) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 265 - 487 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 263 | - | expression tag |
| Ser 264 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 104640.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2040.0 | |
| All* | Total formula weight | 106680.9 |
