4ZO1
Crystal Structure of the T3-bound TR-beta Ligand-binding Domain in complex with RXR-alpha
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (X) | Thyroid hormone receptor beta | polymer | 252 | 28525.0 | 1 | UniProt (P10828) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 1 group A member 2,c-erbA-2,c-erbA-beta |
2 | B (A) | Nuclear receptor coactivator 2 | polymer | 9 | 1162.5 | 1 | UniProt (by SIFTS) (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
3 | C (B) | Retinoic acid receptor RXR-alpha | polymer | 225 | 25224.3 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
4 | D (X) | 3,5,3'TRIIODOTHYRONINE | non-polymer | 651.0 | 1 | Chemie (T3) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 54911.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 651.0 | |
All* | Total formula weight | 55562.8 |