4ZO0

X-ray Structure of AAV-2 Origin Binding Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Protein Rep68	polymer	209	24186.4	3	UniProt (P03132) Pfam (PF08724)	Adeno-associated virus 2 (isolate Srivastava/1982) (AAV-2)
2	D (A)	ISOPROPYL ALCOHOL	non-polymer		60.1	1	Chemie (IPA)
3	E, F, G (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	H, I, J (A, B, C)	water	water		18.0	315	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 206 (UniProt: P03132)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Glu 17	Gly 17	engineered mutation
Ser 151	Cys 151	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	72559.3
Non-Polymers*	Number of molecules	4
	Total formula weight	133.0
All*	Total formula weight	72692.3

*Water molecules are not included.