4ZNC
Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Immunoglobulin G-binding protein A | polymer | 58 | 6695.4 | 3 | UniProt (P38507) Pfam (PF02216) In PDB | Staphylococcus aureus | IgG-binding protein A,Staphylococcal protein A |
2 | D, E, F | Ig gamma-3 chain C region | polymer | 220 | 25124.4 | 3 | UniProt (P01860) Pfam (PF07654) In PDB | Homo sapiens (Human) | HDC,Heavy chain disease protein |
3 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 58 (UniProt: P38507)
D, E, F: 238 - 447 (UniProt: P01860)
PDB | External Database | Details |
---|---|---|
Trp 9 | Gln 278 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Phe 296 | Tyr 226 | conflict |
His 435 | Arg 365 | conflict |
Tyr 436 | Phe 366 | conflict |
Gly 448 | - | expression tag |
Ser 449 | - | expression tag |
Leu 450 | - | expression tag |
Glu 451 | - | expression tag |
His 452 | - | expression tag |
His 453 | - | expression tag |
His 454 | - | expression tag |
His 455 | - | expression tag |
His 456 | - | expression tag |
His 457 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 95459.4 | |
All* | Total formula weight | 95459.4 |