4ZN5
YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase YopH | polymer | 306 | 33530.8 | 1 | UniProt (P15273) Pfam (PF00102) | Yersinia enterocolitica | Virulence protein |
| 2 | B (A) | Divanadate Glycerol ester | non-polymer | 276.0 | 1 | Chemie (DVG) | |||
| 3 | C (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 4 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F (A) | water | water | 18.0 | 453 | Chemie (HOH) |
Sequence modifications
A: 164 - 468 (UniProt: P15273)
| PDB | External Database | Details |
|---|---|---|
| Met 163 | - | initiating methionine |
| Arg 235 | Cys 235 | engineered mutation |
| Tyr 354 | Trp 354 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33530.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 542.1 | |
| All* | Total formula weight | 34072.9 |
