4ZMF

Phosphorylated Aspartate in the Crystal Structure of the Alpha-kinase domain of Myosin-II Heavy Chain Kinase A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Myosin heavy chain kinase A	polymer	307	34606.6	2	UniProt (P42527) Pfam (PF02816)	Dictyostelium discoideum (Slime mold)	MHCK-A
2	C, F (A, B)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505)
3	D, G (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4) PubChem (1061)
4	E, H (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	I, J (A, B)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

A, B: 552 - 841 (UniProt: P42527)

PDB	External Database	Details
Met 535	-	initiating methionine
Gly 536	-	expression tag
Gly 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
Gly 544	-	expression tag
Glu 545	-	expression tag
Asn 546	-	expression tag
Leu 547	-	expression tag
Tyr 548	-	expression tag
Phe 549	-	expression tag
Gln 550	-	expression tag
Gly 551	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69213.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1015.2
All*	Total formula weight	70228.3

*Water molecules are not included.