4ZLO
Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PAK 1 | polymer | 297 | 33339.2 | 2 | UniProt (Q13153) Pfam (PF00069) | Homo sapiens (Human) | Alpha-PAK,p21-activated kinase 1,PAK-1,p65-PAK |
| 2 | C (A) | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | non-polymer | 328.4 | 1 | Chemie (4PV) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66678.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 420.5 | |
| All* | Total formula weight | 67098.9 |
