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4ZLD

Crystal structure of human Roquin-2 ROQ domain in complex with Roquin CDE RNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Roquin-2polymer15517593.31UniProt (Q9HBD1)
Pfam (PF21206)
Pfam (PF18386)
Homo sapiens (Human)Membrane-associated nucleic acid-binding protein,RING finger and CCCH-type zinc finger domain-containing protein 2,RING finger protein 164
2B
(B)
RNA (5'-R(*UP*AP*AP*CP*UP*UP*CP*UP*GP*UP*GP*AP*AP*GP*UP*UP*G)-3')polymer175406.21Homo sapiens
3C, D, E, F
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
4G, H
(A, B)
waterwater18.0186Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight22999.5
Non-Polymers*Number of molecules4
Total formula weight368.4
All*Total formula weight23367.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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