4ZKL
Crystal structure of human histidine triad nucleotide-binding protein 1 (hHINT1) complexed with JB419 (AP4A analog)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histidine triad nucleotide-binding protein 1 | polymer | 126 | 13823.9 | 4 | UniProt (P49773) Pfam (PF01230) | Homo sapiens (Human) | Adenosine 5'-monophosphoramidase,Protein kinase C inhibitor 1,Protein kinase C-interacting protein 1,PKCI-1 |
| 2 | E, G (B, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 3 | F (B) | (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-[2-[[(2S)-3-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl]oxy-2-oxidanyl-propoxy]-sulfanyl-phosphoryl]oxyethyl]oxolane-3,4-diol | non-polymer | 796.7 | 1 | Chemie (JB6) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55295.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1491.1 | |
| All* | Total formula weight | 56786.8 |
