4ZJB

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) in complex with holo-ACP from Helicobacter pylori

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ	polymer	171	19611.7	2	UniProt (Q5G940) Pfam (PF07977) In PDB	Helicobacter pylori	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase,Beta-hydroxyacyl-ACP dehydratase
2	G	Acyl carrier protein	polymer	86	9363.5	1	UniProt (Q5EDC8) Pfam (PF00550) In PDB	Helicobacter pylori	ACP
3	B	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
4	G	4'-PHOSPHOPANTETHEINE	non-polymer		358.3	1	Chemie (PNS)
5		water	water		18.0	72	Chemie (HOH)

Sequence modifications

A, B: 1 - 159 (UniProt: Q5G940)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

G: 1 - 78 (UniProt: Q5EDC8)

PDB	External Database	Details
Gly -7	-	expression tag
Thr -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Met -3	-	expression tag
Gly -2	-	expression tag
Tyr -1	-	expression tag
Leu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48586.8
Non-Polymers*	Number of molecules	2
	Total formula weight	550.5
All*	Total formula weight	49137.3

*Water molecules are not included.