4ZIE
Crystal Structure of core/latch dimer of Bax in complex with BimBH3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Apoptosis regulator BAX | polymer | 168 | 18512.0 | 1 | UniProt (Q07812) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 4,Bcl2-L-4 |
| 2 | B (C) | Bcl-2-like protein 11 | polymer | 26 | 3274.7 | 1 | UniProt (O43521) Pfam (PF08945) | Homo sapiens | Bcl2-L-11,Bcl2-interacting mediator of cell death |
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: Q07812)
| PDB | External Database | Details |
|---|---|---|
| Ser 62 | Cys 62 | engineered mutation |
| Ser 126 | Cys 126 | engineered mutation |
| Ser 167 | - | expression tag |
| Ser 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21786.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 21848.8 |
