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4ZIA

Crystal Structure of STAT3 N-terminal domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Signal transducer and activator of transcription 3polymer12915215.05UniProt (P42227)
Pfam (PF02865)
Mus musculus (Mouse)Acute-phase response factor
2F
(B)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
3G
(D)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
4H
(E)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5I, J, K, L
(A, B, C, D)
waterwater18.063Chemie (HOH)
Sequence modifications
A, B, C, D, E: 3 - 127 (UniProt: P42227)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Gly 1-expression tag
Ser 2-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight76075.2
Non-Polymers*Number of molecules3
Total formula weight129.0
All*Total formula weight76204.3
*Water molecules are not included.

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PDB entries from 2025-05-21

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