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4ZI0

Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region without a chelation to the metal ions in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APolymerase acidic proteinpolymer19122300.51UniProt (P03433)
In PDB
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)RNA-directed RNA polymerase subunit P2
2ASULFATE IONnon-polymer96.11Chemie (SO4)
3AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
4A4-{(E)-[2-(4-chlorophenyl)hydrazinylidene]methyl}benzene-1,2,3-triolnon-polymer278.71Chemie (4P9)
5waterwater18.0203Chemie (HOH)
Sequence modifications
A: 1 - 50 (UniProt: P03433)
PDBExternal DatabaseDetails
Gly -4-expression tag
Pro -3-expression tag
Leu -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
A: 73 - 197 (UniProt: P03433)
PDBExternal DatabaseDetails
Ala 51-linker
Ser 52-linker
Ala 198-expression tag
Ala 199-expression tag
Glu 200-expression tag
Leu 201-expression tag
Ala 202-expression tag
Leu 203-expression tag
Val 204-expression tag
Pro 205-expression tag
Arg 206-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22300.5
Non-Polymers*Number of molecules4
Total formula weight484.6
All*Total formula weight22785.1
*Water molecules are not included.

219140

PDB entries from 2024-05-01

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