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4ZHZ

Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region with expelling one of the metal ions in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APolymerase acidic proteinpolymer19122300.51UniProt (P03433)
In PDB
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)RNA-directed RNA polymerase subunit P2
2A5-(2-chlorobenzyl)-2-hydroxy-3-nitrobenzaldehydenon-polymer291.72Chemie (4P8)
3AMANGANESE (II) IONnon-polymer54.91Chemie (MN)
4ASULFATE IONnon-polymer96.11Chemie (SO4)
5waterwater18.073Chemie (HOH)
Sequence modifications
A: 1 - 50 (UniProt: P03433)
PDBExternal DatabaseDetails
Gly -4-expression tag
Pro -3-expression tag
Leu -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
A: 73 - 197 (UniProt: P03433)
PDBExternal DatabaseDetails
Ala 51-linker
Ser 52-linker
Ala 198-expression tag
Ala 199-expression tag
Glu 200-expression tag
Leu 201-expression tag
Ala 202-expression tag
Leu 203-expression tag
Val 204-expression tag
Pro 205-expression tag
Arg 206-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22300.5
Non-Polymers*Number of molecules4
Total formula weight734.4
All*Total formula weight23034.9
*Water molecules are not included.

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PDB entries from 2024-07-10

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