4ZHZ
Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region with expelling one of the metal ions in the active site
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 4P8 A 301 |
| Chain | Residue |
| A | THR20 |
| A | MN303 |
| A | HOH408 |
| A | HOH414 |
| A | HOH440 |
| A | TYR24 |
| A | HIS41 |
| A | GLU80 |
| A | GLU119 |
| A | ILE120 |
| A | TYR130 |
| A | LYS134 |
| A | 4P8302 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 4P8 A 302 |
| Chain | Residue |
| A | LYS34 |
| A | TYR130 |
| A | LYS137 |
| A | 4P8301 |
| A | HOH412 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 303 |
| Chain | Residue |
| A | GLU80 |
| A | LEU106 |
| A | ASP108 |
| A | GLU119 |
| A | 4P8301 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG179 |
| A | TRP188 |
| A | ARG192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04063, ECO:0000269|PubMed:26252962, ECO:0000269|PubMed:27088785, ECO:0007744|PDB:4YYL, ECO:0007744|PDB:4ZI0, ECO:0007744|PDB:4ZQQ |
| Chain | Residue | Details |
| A | HIS41 | |
| A | ILE120 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04063, ECO:0000269|PubMed:27088785, ECO:0007744|PDB:4YYL, ECO:0007744|PDB:4ZI0, ECO:0007744|PDB:4ZQQ |
| Chain | Residue | Details |
| A | GLU80 | |
| A | ASP108 | |
| A | GLU119 |
