4ZHT
Crystal structure of UDP-GlcNAc 2-epimerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | polymer | 411 | 47075.2 | 4 | UniProt (Q9Y223) Pfam (PF02350) | Homo sapiens (Human) | UDP-GlcNAc-2-epimerase/ManAc kinase |
| 2 | E, G, I, L (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 3 | F, H, J, M (A, B, C, D) | CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID | non-polymer | 614.5 | 4 | Chemie (NCC) PubChem (16219166) PubChem (16760375) PubChem (316) PubChem (18292) PubChem (44329413) PubChem (46936403) PubChem (439172) PubChem (59441420) PubChem (66733818) PubChem (66741952) PubChem (49864022) PubChem (70858351) PubChem (71028647) PubChem (57582904) PubChem (89847360) PubChem (448209) PubChem (92043428) PubChem (92132134) PubChem (129093847) PubChem (11082635) PubChem (11169473) PubChem (9895197) PubChem (11072165) PubChem (11114750) PubChem (154523449) PubChem (131632558) PubChem (146158554) PubChem (152858772) | |||
| 4 | K (C) | 2-acetamido-2-deoxy-beta-D-mannopyranose | non-polymer | 221.2 | 1 | Chemie (BM7) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 405 (UniProt: Q9Y223)
| PDB | External Database | Details |
|---|---|---|
| His 406 | - | expression tag |
| His 407 | - | expression tag |
| His 408 | - | expression tag |
| His 409 | - | expression tag |
| His 410 | - | expression tag |
| His 411 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 188300.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 4295.7 | |
| All* | Total formula weight | 192596.5 |
