4ZHT

Crystal structure of UDP-GlcNAc 2-epimerase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	polymer	411	47075.2	4	UniProt (Q9Y223) Pfam (PF02350) In PDB	Homo sapiens (Human)	UDP-GlcNAc-2-epimerase/ManAc kinase
2	A, B, C, D	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP)
3	A, B, C, D	CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID	non-polymer		614.5	4	Chemie (NCC)
4	C	2-acetamido-2-deoxy-beta-D-mannopyranose	non-polymer		221.2	1	Chemie (BM7)
5		water	water		18.0	331	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 405 (UniProt: Q9Y223)

PDB	External Database	Details
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	188300.8
Non-Polymers*	Number of molecules	9
	Total formula weight	4295.7
All*	Total formula weight	192596.5

*Water molecules are not included.