4ZHT
Crystal structure of UDP-GlcNAc 2-epimerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | polymer | 411 | 47075.2 | 4 | UniProt (Q9Y223) Pfam (PF02350) | Homo sapiens (Human) | UDP-GlcNAc-2-epimerase/ManAc kinase |
| 2 | E, G, I, L (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) | |||
| 3 | F, H, J, M (A, B, C, D) | CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID | non-polymer | 614.5 | 4 | Chemie (NCC) | |||
| 4 | K (C) | 2-acetamido-2-deoxy-beta-D-mannopyranose | non-polymer | 221.2 | 1 | Chemie (BM7) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 405 (UniProt: Q9Y223)
| PDB | External Database | Details |
|---|---|---|
| His 406 | - | expression tag |
| His 407 | - | expression tag |
| His 408 | - | expression tag |
| His 409 | - | expression tag |
| His 410 | - | expression tag |
| His 411 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 188300.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 4295.7 | |
| All* | Total formula weight | 192596.5 |
