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4ZHI

Eg5 motor domain mutant E162S

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Kinesin-like protein KIF11polymer36941126.72UniProt (P52732)
Pfam (PF00225)
Homo sapiens (Human)Kinesin-like protein 1,Kinesin-like spindle protein HKSP,Kinesin-related motor protein Eg5,Thyroid receptor-interacting protein 5,TRIP-5
2C, D
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
3E, F
(A, B)
waterwater18.0308Chemie (HOH)
Sequence modifications
A, B: 1 - 369 (UniProt: P52732)
PDBExternal DatabaseDetails
Ser 162Glu 162engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82253.4
Non-Polymers*Number of molecules2
Total formula weight854.4
All*Total formula weight83107.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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