4ZGM
Crystal structure of Semaglutide peptide backbone in complex with the GLP-1 receptor extracellular domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucagon-like peptide 1 receptor | polymer | 122 | 14325.8 | 1 | UniProt (P43220) Pfam (PF02793) | Homo sapiens (Human) | GLP-1R |
| 2 | B (B) | Semaglutide peptide backbone; 8Aib,34R-GLP-1(7-37)-OH | polymer | 31 | 3401.7 | 1 | Pfam (PF00123) UniProt (by SIFTS) (P01275) | Homo sapiens | |
| 3 | C, D (A, B) | 3,6,9,12,15,18-hexaoxahexacosan-1-ol | non-polymer | 394.5 | 2 | Chemie (32M) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 17727.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 789.1 | |
| All* | Total formula weight | 18516.7 |
