4ZDQ
Crystal Structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Burkholderia thailandensis complexed with CTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | polymer | 241 | 25821.4 | 4 | UniProt (Q2SWT6) Pfam (PF01128) | Burkholderia thailandensis | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase,MEP cytidylyltransferase,MCT |
| 2 | E, P (A, D) | CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 483.2 | 2 | Chemie (CTP) | |||
| 3 | F, Q (A, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H, I, J, K... (A, C, D) | ACETATE ION | non-polymer | 59.0 | 10 | Chemie (ACT) | |||
| 5 | O (C) | CACODYLIC ACID | non-polymer | 138.0 | 1 | Chemie (CAD) | |||
| 6 | T (D) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 236 (UniProt: Q2SWT6)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103285.5 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1835.5 | |
| All* | Total formula weight | 105121.0 |
