4ZD4
Catalytic domain of Sst2 F403W mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AMSH-like protease sst2 | polymer | 197 | 22020.8 | 2 | UniProt (Q9P371) Pfam (PF01398) | Schizosaccharomyces pombe (Fission yeast) | Suppressor of ste12 deletion protein 2 |
| 2 | C, D, E, F, G... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 3 | H (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | I, J, R, S (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | Q (B) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 6 | T, U (A, B) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A, B: 245 - 435 (UniProt: Q9P371)
| PDB | External Database | Details |
|---|---|---|
| Gly 239 | - | expression tag |
| Pro 240 | - | expression tag |
| Leu 241 | - | expression tag |
| Gly 242 | - | expression tag |
| Ser 243 | - | expression tag |
| Met 244 | - | expression tag |
| Trp 403 | Phe 403 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44041.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1220.8 | |
| All* | Total formula weight | 45262.3 |
