4ZCW
Structure of Human Enolase 2 in complex with SF2312
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Gamma-enolase | polymer | 440 | 48149.3 | 2 | UniProt (P09104) Pfam (PF03952) Pfam (PF00113) | Homo sapiens (Human) | 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, NSE |
| 2 | C, F (A, B) | [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid | non-polymer | 197.1 | 2 | Chemie (4NG) | |||
| 3 | D, E, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 595 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 434 (UniProt: P09104)
| PDB | External Database | Details |
|---|---|---|
| His 435 | - | expression tag |
| His 436 | - | expression tag |
| His 437 | - | expression tag |
| His 438 | - | expression tag |
| His 439 | - | expression tag |
| His 440 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96298.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 491.4 | |
| All* | Total formula weight | 96789.9 |
