4Z96

Crystal structure of DNMT1 in complex with USP7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ubiquitin carboxyl-terminal hydrolase 7	polymer	530	61887.3	1	UniProt (Q93009) Pfam (PF12436) Pfam (PF14533)	Homo sapiens (Human)	Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
2	B (C)	DNA (cytosine-5)-methyltransferase 1	polymer	33	3457.9	1	UniProt (P26358)	Homo sapiens (Human)	Dnmt1,CXXC-type zinc finger protein 9,DNA methyltransferase HsaI,M.HsaI,MCMT

Sequence modifications

A: 560 - 1083 (UniProt: Q93009)

PDB	External Database	Details
Ser 554	-	expression tag
Gly 555	-	expression tag
Pro 556	-	expression tag
Leu 557	-	expression tag
Gly 558	-	expression tag
Ser 559	-	expression tag

C: 1097 - 1129 (UniProt: P26358)

PDB	External Database	Details
Ser 1097	Glu 1097	conflict
Trp 1099	Pro 1099	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65345.2
All*	Total formula weight	65345.2

*Water molecules are not included.