4Z94

Actin Complex With a Chimera of Tropomodulin-1 and Leiomodin-1 Actin-Binding Site 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Actin, alpha skeletal muscle	polymer	377	42110.0	1	UniProt (P68135) Pfam (PF00022)	Oryctolagus cuniculus (Rabbit)	Alpha-actin-1
2	B (G)	Gelsolin, Tropomodulin-1, Leiomodin-1 chimera	polymer	326	36533.5	1	UniProt (P06396) UniProt (P28289) UniProt (P29536) Pfam (PF00626)	Homo sapiens (Human)	AGEL, Actin-depolymerizing factor, ADF, Brevin,Erythrocyte tropomodulin, E-Tmod,64 kDa autoantigen 1D, 64 kDa autoantigen 1D3, 64 kDa autoantigen D1, Leiomodin, muscle form, Smooth muscle leiomodin, SM-Lmod, Thyroid-associated ophthalmopathy autoantigen
3	C (A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
4	D, E, F (A, G)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
5	G, H (A, G)	water	water		18.0	182	Chemie (HOH)

Sequence modifications

G: 1 - 125 (UniProt: P06396)

PDB	External Database	Details
Gly 126	-	linker
Gly 1152	-	linker
Ser 1153	-	linker
Gly 1154	-	linker
Gly 1155	-	linker
Ser 1156	-	linker
Gly 1157	-	linker
Gly 1158	-	linker
Ser 1159	-	linker

G: 1160 - 1228 (UniProt: P28289)
G: 1229 - 1486 (UniProt: P29536)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78643.4
Non-Polymers*	Number of molecules	4
	Total formula weight	627.4
All*	Total formula weight	79270.8

*Water molecules are not included.