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4Z80

Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
EGF family domain-containing proteinpolymer50855659.32UniProt (V4YLU4)
Pfam (PF02430)
Pfam (PF07974)
UniProt (by SIFTS) (S7UIL3)
Toxoplasma gondii
2B, D
(C, D)
Cytoadherence-linked asexual proteinpolymer373633.12UniProt (B6KQU6)Toxoplasma gondii
3E, F, G, L
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
4H, I, J
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
5K
(B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
6M, N, O, P
(A, C, B, D)
waterwater18.01361Chemie (HOH)
Sequence modifications
A, B: 58 - 553 (UniProt: V4YLU4)
PDBExternal DatabaseDetails
Gly 53-expression tag
Ser 54-expression tag
Ala 55-expression tag
Met 56-expression tag
Gly 57-expression tag
Ala 554-expression tag
Ala 555-expression tag
Ala 556-expression tag
Leu 557-expression tag
Val 558-expression tag
Pro 559-expression tag
Arg 560-expression tag
C, D: 1292 - 1324 (UniProt: B6KQU6)
PDBExternal DatabaseDetails
Gly 1288-expression tag
Ser 1289-expression tag
Ala 1290-expression tag
Ser 1291-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight118584.7
Non-Polymers*Number of molecules8
Total formula weight877.8
All*Total formula weight119462.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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