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4Z7G

Crystal structure of human IRE1 cytoplasmic kinase-RNase region - apo

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine/threonine-protein kinase/endoribonuclease IRE1polymer41647755.82UniProt (O75460)
Pfam (PF00069)
Pfam (PF06479)
Homo sapiens (Human)Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a
2C, D
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
3E, F
(A, B)
waterwater18.015Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight95511.6
Non-Polymers*Number of molecules2
Total formula weight46.0
All*Total formula weight95557.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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