4Z4P
Structure of the MLL4 SET Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase 2D | polymer | 166 | 19704.4 | 1 | UniProt (O14686) Pfam (PF00856) | Homo sapiens (Human) | Lysine N-methyltransferase 2D,ALL1-related protein,Myeloid/lymphoid or mixed-lineage leukemia protein 2 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | D (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 5382 - 5536 (UniProt: O14686)
| PDB | External Database | Details |
|---|---|---|
| Met 5379 | - | initiating methionine |
| Thr 5380 | - | expression tag |
| Leu 5381 | - | expression tag |
| Glu 5522 | Lys 5525 | engineered mutation |
| Lys 5537 | - | expression tag |
| Gly 5538 | - | expression tag |
| His 5539 | - | expression tag |
| His 5540 | - | expression tag |
| His 5541 | - | expression tag |
| His 5542 | - | expression tag |
| His 5543 | - | expression tag |
| His 5544 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19704.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 449.8 | |
| All* | Total formula weight | 20154.2 |
