4Z46
X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Lysozyme C | polymer | 129 | 14331.2 | 1 | UniProt (P00698) Pfam (PF00062) | Gallus gallus (Chicken) | 1,4-beta-N-acetylmuramidase C,Allergen Gal d IV |
2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
3 | D, E, F, G, H... (A) | NITRATE ION | non-polymer | 62.0 | 9 | Chemie (NO3) | |||
4 | M, N (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
5 | O (A) | CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II) | non-polymer | 309.3 | 1 | Chemie (1PT) | |||
6 | P (A) | Cisplatin | non-polymer | 300.0 | 1 | Chemie (CPT) | |||
7 | Q (A) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 14331.2 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 1337.5 | |
All* | Total formula weight | 15668.6 |