4Z30

Crystal structure of the ROQ domain of human Roquin-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Roquin-2	polymer	325	36676.1	1	UniProt (Q9HBD1) Pfam (PF21206) Pfam (PF18386) In PDB	Homo sapiens (Human)	Membrane-associated nucleic acid-binding protein,RING finger and CCCH-type zinc finger domain-containing protein 2,RING finger protein 164
2	A	UNKNOWN ATOM OR ION	non-polymer			4	Chemie (UNX)
3		water	water		18.0	13	Chemie (HOH)

Sequence modifications

A: 87 - 404 (UniProt: Q9HBD1)

PDB	External Database	Details
Met 86	-	engineered mutation
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36676.1
Non-Polymers*	Number of molecules	4
	Total formula weight	0.0
All*	Total formula weight	36676.1

*Water molecules are not included.