4Z0R
Crystal Structure of the CW domain of ZCWPW2 mutant F78R in complex with histone H3 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Zinc finger CW-type PWWP domain protein 2 | polymer | 59 | 7088.8 | 3 | UniProt (Q504Y3) Pfam (PF07496) | Homo sapiens (Human) | zcwpw2 |
| 2 | D (D) | Histone H3.1 | polymer | 16 | 1605.9 | 1 | UniProt (P68431) | Homo sapiens | Histone H3 |
| 3 | AA, E, R (C, A, B) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | BA, CA, DA, EA, FA... (C, D, A, B) | UNKNOWN ATOM OR ION | non-polymer | 24 | Chemie (UNX) | ||||
| 6 | Z (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B, C: 21 - 78 (UniProt: Q504Y3)
D: 1 - 15 (UniProt: P68431)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| Arg 78 | Phe 78 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Nh2 16 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 22872.1 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 354.4 | |
| All* | Total formula weight | 23226.5 |
