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4YZC

Crystal structure of pIRE1alpha in complex with staurosporine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine/threonine-protein kinase/endoribonuclease IRE1polymer40546850.52UniProt (O75460)
Pfam (PF00069)
Pfam (PF06479)
Homo sapiens (Human)Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a
2C, D
(A, B)
STAUROSPORINEnon-polymer466.52Chemie (STU)
3E, F
(A, B)
waterwater18.058Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight93701.0
Non-Polymers*Number of molecules2
Total formula weight933.1
All*Total formula weight94634.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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