4YXP
The structure of the folded domain of the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | mRNA export factor | polymer | 275 | 30098.5 | 2 | UniProt (P10238) Pfam (PF05459) | Human herpesvirus 1 (strain 17) (HHV-1) | Multifunctional viral protein, Immediate-early protein IE63,Infected cell protein 27,ICP27,VMW63 |
| 2 | C, D (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence modifications
A, B: 241 - 512 (UniProt: P10238)
| PDB | External Database | Details |
|---|---|---|
| Gly 238 | - | expression tag |
| Pro 239 | - | expression tag |
| Gly 240 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60197.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 60327.9 |
