4YWU

Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Succinic semialdehyde dehydrogenase	polymer	465	51861.2	2	Pfam (PF00171) UniProt (by SIFTS) (A0A0J9X1M8)	Streptococcus pyogenes MGAS1882	Succinate-semialdehyde dehydrogenase, NADP+-dependent succinic semialdehyde dehydrogenase
2	C, F (A, B)	4-oxobutanoic acid	non-polymer		102.1	2	Chemie (SSN)
3	D, E, G, H (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	I, J (A, B)	water	water		18.0	590	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103722.5
Non-Polymers*	Number of molecules	6
	Total formula weight	588.4
All*	Total formula weight	104310.9

*Water molecules are not included.