4YW5
Crystal Structure of Streptococcus pneumoniae NanC, complex with oseltamivir carboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neuraminidase C | polymer | 659 | 73978.6 | 2 | UniProt (A0A0H2UQE4) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Putative neuraminidase |
| 2 | C, J (A, B) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 2 | Chemie (G39) | |||
| 3 | D, E, F, G, H... (A, B) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 4 | I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A, B: 83 - 740 (UniProt: A0A0H2UQE4)
| PDB | External Database | Details |
|---|---|---|
| Leu 741 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147957.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1459.6 | |
| All* | Total formula weight | 149416.8 |
