4YW1
Crystal Structure of Streptococcus pneumoniae NanC, complex with Neu5Ac and Neu5Ac2en following soaking with 3'SL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neuraminidase C | polymer | 659 | 73978.6 | 2 | UniProt (A0A0H2UQE4) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Putative neuraminidase |
| 2 | C, G (A, B) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 2 | Chemie (SIA) | |||
| 3 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 4 | E, I (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) PubChem (8117) | |||
| 5 | F (B) | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 291.3 | 1 | Chemie (DAN) PubChem (65309) PubChem (196123) PubChem (1553) PubChem (440392) PubChem (492456) PubChem (68019401) PubChem (132002898) PubChem (133688885) PubChem (13728878) PubChem (15956564) PubChem (44314809) PubChem (44353094) PubChem (44387099) PubChem (57673682) PubChem (50986297) PubChem (5329058) PubChem (71299570) PubChem (71312796) PubChem (93616863) PubChem (101008065) PubChem (102094437) PubChem (44299597) PubChem (44305374) PubChem (44629965) PubChem (49819354) | |||
| 6 | H (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 857 | Chemie (HOH) |
Sequence modifications
A, B: 83 - 740 (UniProt: A0A0H2UQE4)
| PDB | External Database | Details |
|---|---|---|
| Leu 741 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147957.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1309.1 | |
| All* | Total formula weight | 149266.3 |
