4YUX
Crystal structure of Trypanosoma cruzi spermidine synthase in complex with 2H-1,4-benzothiazin-3-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Spermidine synthase, putative | polymer | 304 | 34103.7 | 2 | UniProt (Q4DA73) Pfam (PF17284) Pfam (PF01564) | Trypanosoma cruzi (strain CL Brener) | |
| 2 | C, E (A, B) | 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE | non-polymer | 356.4 | 2 | Chemie (S4M) | |||
| 3 | D, F (A, B) | 2H-1,4-benzothiazin-3-amine | non-polymer | 164.2 | 2 | Chemie (4JT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 296 (UniProt: Q4DA73)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68207.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1041.3 | |
| All* | Total formula weight | 69248.8 |
