4YU0
Crystal structure of a tetramer of GluA2 TR mutant ligand binding domains bound with glutamate at 1.26 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2,Glutamate receptor 2 | polymer | 263 | 29187.7 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | C, I (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 3 | D, E, F, J, K... (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 4 | G, H, M, N (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 822 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
A, B: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Thr 201 | Glu 734 | engineered mutation |
| Arg 256 | Tyr 789 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58375.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1288.6 | |
| All* | Total formula weight | 59664.0 |
