4YT7
Factor VIIa in complex with the inhibitor 2-(2-{(R)-[(4-carbamimidoylphenyl)amino][5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl]methyl}-1H-imidazol-4-yl)benzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Coagulation factor VII (heavy chain) | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (Human) | Factor VIIa heavy chain, activated Factor VIIa heavy chain, Proconvertin, Serum prothrombin conversion accelerator, SPCA |
| 2 | B (L) | Coagulation factor VII (light chain) | polymer | 57 | 6272.1 | 1 | UniProt (P08709) Pfam (PF14670) | Homo sapiens (Human) | Factor VIIa light chain, Proconvertin, Serum prothrombin conversion accelerator, SPCA |
| 3 | C (H) | 2-[2-[(R)-[(4-carbamimidoylphenyl)amino]-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)methyl]-1H-imidazol-4-yl]benzamide | non-polymer | 530.6 | 1 | Chemie (4K1) | |||
| 4 | D (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F, G, H (H) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | I, J (H) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | K, L (H, L) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34375.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1139.1 | |
| All* | Total formula weight | 35514.5 |
