4YT1
Human PPAR Gamma Ligand Binding Domain in complex with a Gammma Selective Synthetic Partial Agonist MEKT76
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 286 | 32530.7 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B | N-(benzylsulfonyl)-4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)benzamide | non-polymer | 544.6 | 1 | Chemie (JJB) | |||
| 3 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 195 - 476 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 191 | - | expression tag |
| Ser 192 | - | expression tag |
| His 193 | - | expression tag |
| Met 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65061.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 544.6 | |
| All* | Total formula weight | 65605.9 |
