4YRE
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with (2-bromophenyl)methanol (Chem 145)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Histidyl-tRNA synthetase | polymer | 456 | 51185.6 | 2 | UniProt (Q4DA54) Pfam (PF13393) Pfam (PF03129) In PDB | Trypanosoma cruzi (strain CL Brener) | |
2 | A, B | HISTIDINE | non-polymer | 156.2 | 2 | Chemie (HIS) | |||
3 | A, B | (2-bromophenyl)methanol | non-polymer | 187.0 | 2 | Chemie (4HR) | |||
4 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 6 | Chemie (DMS) | |||
5 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
6 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
7 | water | water | 18.0 | 336 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 478 (UniProt: Q4DA54)
PDB | External Database | Details |
---|---|---|
Met -21 | - | initiating methionine |
Ala -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
Met -13 | - | expression tag |
Gly -12 | - | expression tag |
Thr -11 | - | expression tag |
Leu -10 | - | expression tag |
Glu -9 | - | expression tag |
Ala -8 | - | expression tag |
Gln -7 | - | expression tag |
Thr -6 | - | expression tag |
Gln -5 | - | expression tag |
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 102371.2 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1821.7 | |
All* | Total formula weight | 104192.9 |