Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue HIS A 501 |
| Chain | Residue |
| A | GLU126 |
| A | GLY359 |
| A | PHE360 |
| A | GLY361 |
| A | HOH620 |
| A | HOH662 |
| A | THR128 |
| A | GLN170 |
| A | ASN172 |
| A | ASP174 |
| A | LEU316 |
| A | TYR318 |
| A | TYR319 |
| A | TYR342 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 4HR A 502 |
| Chain | Residue |
| A | PRO125 |
| A | CYS154 |
| A | TRP155 |
| A | ARG156 |
| A | ARG165 |
| A | GLU167 |
| A | HIS168 |
| A | HOH603 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 503 |
| Chain | Residue |
| A | TRP193 |
| A | ARG196 |
| A | SER197 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 504 |
| Chain | Residue |
| A | GLU96 |
| A | LEU97 |
| A | ILE99 |
| A | ARG100 |
| A | TYR349 |
| A | HOH608 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | ARG165 |
| A | HIS168 |
| A | ARG334 |
| A | GLY363 |
| A | CYS365 |
| A | VAL366 |
| A | HOH603 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | ARG196 |
| A | SER201 |
| A | SER202 |
| A | TRP305 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 507 |
| Chain | Residue |
| A | ARG69 |
| A | HIS76 |
| A | HOH601 |
| B | ARG69 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | THR115 |
| A | GLY117 |
| B | TYR157 |
| B | ARG166 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue HIS B 501 |
| Chain | Residue |
| B | GLU126 |
| B | THR128 |
| B | GLN170 |
| B | ASN172 |
| B | ASP174 |
| B | LEU316 |
| B | TYR318 |
| B | TYR319 |
| B | GLY338 |
| B | TYR342 |
| B | GLY359 |
| B | PHE360 |
| B | GLY361 |
| B | HOH609 |
| B | HOH621 |
| B | HOH670 |
| B | HOH702 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue 4HR B 502 |
| Chain | Residue |
| B | PRO125 |
| B | CYS154 |
| B | TRP155 |
| B | ARG156 |
| B | ARG165 |
| B | GLU167 |
| B | HIS168 |
| B | HOH601 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 503 |
| Chain | Residue |
| B | TRP193 |
| B | ARG196 |
| B | SER197 |
| B | TYR302 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 504 |
| Chain | Residue |
| B | GLU96 |
| B | LEU97 |
| B | ILE99 |
| B | ARG100 |
| B | TYR349 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue DMS B 505 |
| Chain | Residue |
| A | VAL253 |
| A | LEU254 |
| A | HOH717 |
| B | VAL472 |
| B | ARG476 |
| B | HOH613 |
| B | HOH624 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 506 |
| Chain | Residue |
| A | PRO473 |
| A | ARG476 |
| B | ALA102 |
| B | PRO231 |
| B | VAL234 |
| B | HOH669 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 507 |
| Chain | Residue |
| B | ARG334 |
| B | GLY363 |
| B | ASP364 |
| B | CYS365 |
| B | VAL366 |
| B | HOH601 |
| B | ARG165 |
| B | HIS168 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 508 |
| Chain | Residue |
| B | ARG196 |
| B | SER201 |
| B | SER202 |
| B | TRP305 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 509 |
| Chain | Residue |
| A | TYR157 |
| A | ARG166 |
| B | THR115 |
| B | LYS116 |
| B | HIS119 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 510 |
| Chain | Residue |
| B | VAL422 |
| B | PHE426 |
| B | ALA437 |
| B | LYS453 |
| B | HOH634 |
