4YQX
Mouse IL-2 Bound to JES6-1 scFv Fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (H, N) | JES6-1 VH domain | polymer | 123 | 13802.2 | 2 | Rattus norvegicus (Mouse) | ||
| 2 | B, E (L, O) | JES6-1 VL domain | polymer | 118 | 12648.1 | 2 | Rattus norvegicus (Mouse) | ||
| 3 | C, F (A, M) | Interleukin-2 | polymer | 130 | 14956.1 | 2 | UniProt (P04351) Pfam (PF00715) | Mus musculus (Mouse) | IL-2, T-cell growth factor, TCGF |
| 4 | G (B) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 716.7 | 1 | In PDB GlyTouCan (G63564LA) | |||
| 5 | H (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | I, J, K, L, M... (H, L, A, N, O...) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A, M: 27 - 149 (UniProt: P04351)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Pro 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Ala 150 | - | expression tag |
| Ala 151 | - | expression tag |
| Ala 152 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 82812.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| All* | Total formula weight | 83953.7 |
