4YON

P-Rex1:Rac1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein	polymer	405	45641.2	1	UniProt (Q8TCU6) Pfam (PF00621) Pfam (PF22697)	Homo sapiens (Human)	PtdIns(3,4,5)-dependent Rac exchanger 1
2	B (B)	Ras-related C3 botulinum toxin substrate 1	polymer	179	19897.0	1	UniProt (P63000) Pfam (PF00071)	Homo sapiens (Human)	Cell migration-inducing gene 5 protein,Ras-like protein TC25,p21-Rac1
3	C, D (A, B)	water	water		18.0	780	Chemie (HOH)

Sequence modifications

A: 1 - 404 (UniProt: Q8TCU6)

PDB	External Database	Details
Gly 0	-	expression tag

B: 1 - 177 (UniProt: P63000)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Val 12	Gly 12	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65538.2
All*	Total formula weight	65538.2

*Water molecules are not included.